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We\u2019ve put together some commonly asked questions about Diagnostic Green’s IC-Green\u00ae (indocyanine green for injection) for intravenous or interstitial use. Indocyanine Green has six hours of stability when reconstituted as detailed in the package insert. Diagnostic Green has no additional stability data beyond that.<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t IC-Green\u00ae (indocyanine green for injection) is an optical imaging agent indicated for:<\/p> IC Green\u00ae Injection (ICG) contains up to 5% sodium iodide.<\/p> Allergic reactions have been reported in patients with and without a history of allergy to iodides.<\/p> It is known that in very rare cases (<1\/10,000), Indocyanine Green (ICG) can cause nausea and anaphylactic reactions. Always have cardiopulmonary resuscitation personnel and equipment readily available and monitor patients.<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t After injection, Indocyanine Green (ICG) fluorescence can be visualized in less than one minute.<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t Indicator-Dilution Studies. For visualization of vessels, blood flow and tissue perfusion (2.5mg\/mL solution)<\/p> For visualization of extrahepatic biliary ducts in adults and pediatric patients aged 12 years and older (2.5 mg\/mL solution)<\/p> For lymphatic mapping and cervical and uterine cancer in adults (1.25 mg\/mL solution)<\/p> For ophthalmic angiography<\/p> The dosage depends on the intended application and the weight of the patient. For details, please see the instructions for use at<\/p> IC-Green\u00ae (indocyanine green for injection) Package Insert.<\/a><\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t IC-Green\u00ae (indocyanine green for injection) Package configuration: available in vial kit of 6 vials of the lyophilized green powder and 6 vials of 10 mL Sterile Water for Injection, USP,\u00a0 Vial Strength: 25 mg.<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t For injection: 25 mg of indocyanine green as a <\/span>lyophilized<\/span>, green powder for reconstitution in a single-patient-use vial<\/span><\/span>.<\/span><\/span><\/p> \u2013 for more information go to\u00a0Product Information Leaflet IC-Green\u00ae (indocyanine green for injection) Package Insert.<\/a><\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t No. IC-Green\u00ae (indocyanine green for injection) is a sterile product which is injected intravenously or interstitially. This medicinal product is for single patient use only.<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t When bound to proteins in plasma or in lymph fluid, indocyanine green absorbs light in the near-infrared region with peak absorption at 805 nm and emits fluorescence (light) at a slightly longer wavelength, with peak emission at 830 nm. Fluorescence imaging devices provide external energy as near infrared light for indocyanine green to absorb, resulting in excitation of the indocyanine green, and the emitted light (fluorescence) is transferred from the field of view to an image on a monitor. These optical properties of indocyanine green are utilized in fluorescence imaging of the micro- and macro- vasculature, blood flow and tissue perfusion, the extrahepatic biliary ducts, and for lymphatic mapping of lymph nodes and lymphatic vessels.<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t Indocyanine Green for Injection (ICG) is approved for intravenous injection via an injection needle, a central or peripheral catheter or cardiac catheter and also interstitially for lymphatic mapping.\u00a0<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t \u00a0IC-Green\u00ae Injection (ICG) is a tricarbocyanine dye, is indicated:<\/span><\/p> For injection: 25 mg of indocyanine green as a lyophilized, green powder for reconstitution in a single-patient-use vial.<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t IC-Green\u00ae (indocyanine green for injection)\u00a0 is approved for use in the USA and available via the following wholesalers.\u00a0<\/p>
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Under sterile conditions, the IC-Green\u00ae Injection (ICG) powder should be dissolved with the Sterile Water provided and the solution used within 6 hours after it is prepared.<\/p>