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We\u2019ve put together some commonly asked questions about Fluorescence Guided Surgery. Fluorescence Guided Surgery (FGS) is a medical imaging technique that uses fluorescent dye to identify anatomic structures during surgical procedures.\u00a0 Fluorescence Guided Surgery (FGS) typically involves the use of a Fluorescent Dye, and a special camera system to visualize the fluorescence. The most commonly used fluorescent agent is Indocyanine Green (ICG). ICG was approved by the US FDA in 1959, has an excellent safety profile and can be used in a variety of surgical applications.<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t Surgery is among one of the most common treatments prescribed for acute and chronic diseases with as many as 40 million surgeries performed annually in the United States alone. Much of human surgery is performed without any image guidance where the surgeon has only direct visualizationas as their guide. Fluorescence Guided Surgery (FGS), (also called ‘Fluorescence image-guided surgery’) is a medical imaging technique used to detect fluorescently labelled structures during surgery and provide real time assessment of blood flow to these structures. FGS guides the surgical procedure and provides the surgeon with real time visualization of their operating field.<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t Fluorescence is a phenomenon of light emission with a Despite many advances in preoperative medical imaging such as CT and MRI scans, surgeons still almost exclusively operate under white (visible) light during their procedures and must rely on their ability to see and feel target tissues. Unfortunately, most human tissue looks very similar under white light, and it can be very difficult to distinguish one tissue from another or to completely remove a target tissue such as a tumor. In addition, a surgeon can only see the uppermost layer of tissue under white light while tissues and structures underneath will remain hidden.<\/p> Fluorescence Guided Surgery (FGS) essentially gives the surgeons the ability to \u2018see\u2019 these invisible structures by using a different wavelength of light. By combining this visual ability with the special dyes that fluoresce in those wavelengths, surgeons can much more precisely target or avoid certain organs or tissues. In addition, the near-infrared light used in FGS can more easily penetrate human tissues, allowing surgeons to see \u2018through\u2019 layers of tissue and organs. FGS has the added advantage of being a real-time imaging process. Whereas traditional imaging like X-Rays, CT Scans, and MRI scans can provide excellent images, they are all limited to providing static images.<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t The most used fluorescent marker is Indocyanine Green (ICG). ICG is a tricarbocyanine dye with both hydrophilic and lipophilic properties. Developed in the 1950s, Indocyanine Green (ICG) is a water-soluble fluorescent molecule with a proven safety profile that binds to plasma proteins. ICG is used as a marker in the assessment of vascular perfusion (or blood flow) to the tissues and organs in many areas of medicine. The light required to trigger fluorescence is generated by a near-infrared light source attached to a camera, which tracks and documents both absorption and fluorescence in real time.<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t Yes, Indocyanine Green, ICG is available in many territories worldwide. Marketed in many territories in Europe under the name Verdye and in the USA by the name Indocyanine Green, for Injection, USP & IC Green\u00ae (indocyanine green for injection), it is sold internationally by Diagnostic Green.\u00a0 Diagnostic Green is the leading provider of trusted high quality Indocyanine Green (ICG) for physicians worldwide.<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t Both the excitation and fluorescent lights are in the Live images from the fluorescent dye and the surgical field are obtained using a combination of filters, lenses and cameras. During open surgery, hand-held devices are usually preferred for their ease of use and mobility. Examples of hand-held systems include IC-Flow, PDE Neo and Fluobeam. Fluorescence Guided Surgery, FGS can also be performed using minimally invasive devices such as laparoscopes or endoscopes. In this case, a system of filters, lenses and cameras is attached to the end of the probe.\u00a0 Examples of endoscopic camera systems include Visera Elite, EleVision and Rubina\u2122. Fluorescence Guided Surgery (FGS) devices can also be implemented for robotic surgery (for example in the da Vinci Surgical System).<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t
If you can\u2019t find the answer to your question please contact us <\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
certain wavelength from a material when it is irradiated by light with another
wavelength. The irradiated and emitted lights are called \u201cExcitation Light\u201d and
\u201cFluorescence Light\u201d respectively. The material is called a \u201cFluorescent
Substance\u201d or \u201cfluorophore\u201d.<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t
near-infrared region where light absorption by hemoglobin (and water) is small,
so the light can travel long distances in the human body.<\/span>\u00a0 <\/span>ICG can be excited and emits fluorescence
which can be visualized by appropriate camera systems approved worldwide.<\/span><\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t