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{"id":2101,"date":"2020-08-31T14:27:56","date_gmt":"2020-08-31T14:27:56","guid":{"rendered":"https:\/\/diagnosticgreen.com\/am\/?page_id=2101"},"modified":"2025-06-25T08:24:17","modified_gmt":"2025-06-25T08:24:17","slug":"icg-use-in-ophthalmology","status":"publish","type":"page","link":"https:\/\/diagnosticgreen.com\/am\/icg-use-in-ophthalmology\/","title":{"rendered":"ICG Use in Ophthalmology"},"content":{"rendered":"\t\t
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Use of Indocyanine Green for Injection USP (ICG) in\u00a0<\/h1>

Ophthalmology<\/h1>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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\n\t\t\t\t\t\t\t\t\tIndocyanine Green Angiography (ICGA) is the gold standard in diagnosing a number of serious eye conditions and is a\nkey diagnostic tool used by ophthalmology specialists worldwide.\n

ICGA is particularly useful in the differential diagnosis of Polypoidal Choroidal Vasculopathy (PCV),\nCentral Serous Chorioretinopathy (CSCR), and Retinal Angiomatous Proliferation (RAP), which can be misdiagnosed\nas nAMD (Neovascular Age-related Macular Degeneration)1.\u00a0<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\"Green\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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Key Features<\/span><\/h2>

Indocyanine Green for Injection USP (ICG)) is a tricarbocyanine dye with both hydrophilic and lipophilic properties.<\/p>

The retention of ICG in the fenestrated choroidal circulation, combined with its low permeability, makes ICG angiography ideal for viewing the choroidal blood vessels.\u00a0<\/span><\/p>

Once injected, the ICG binds to plasma proteins and quickly circulates to the choroid layer, delineating the choroidal <\/a>veins within 15-20 secs. <\/span><\/p>

Indocyanine Green<\/a> for Injection is cleared exclusively through the liver and then excreted through the bile. It does not undergo metabolism. Verdye has an excellent safety profile and adverse reactions occur very rarely (<1\/10,000).<\/span><\/p>

Using ICGA at initial presentation helps identify disorders of the choroidal circulation, allowing differential treatment approaches that may improve outcomes and safety for patients.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t

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