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We\u2019ve put together some commonly asked questions about Fluorescence Guided Surgery.\u00a0 Fluorescence Guided Surgery (FGS) is a medical imaging technique that uses fluorescent dye to identify anatomic structures during surgical procedures.\u00a0 Fluorescence Guided Surgery (FGS) typically involves the use of a fluorescent dye, and a special camera system to visualize the fluorescence. The most commonly used fluorescent agent is Indocyanine Green (ICG). ICG was approved by the US FDA in 1959, has an excellent safety profile and can be used in a variety of surgical applications<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t Surgery is among one of the most common treatments Fluorescence is a phenomenon of light emission with Despite many advances in preoperative medical Fluorescence Guided Surgery (FGS) essentially gives The most used fluorescent marker is Indocyanine Indocyanine Green (ICG) is used as a marker in the Yes, Indocyanine Green (ICG) is available in many \u00a0<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t Indocyanine Green (ICG) is intended for intravenous Indocyanine Green (ICG) has been used for more 50 years Both the excitation and fluorescent lights are in Live images from the fluorescent dye and the \u201cIntraoperative fluorescence imaging offers the \u201cThe use of fluorescence is an absolute There are several possible reasons why ICG fluorescence may not be visible. Below are common issues and solutions:<\/p> Still Having Issues?<\/strong><\/p> If none of these solutions resolve the problem, please reach out to info@diagnosticgreen.com<\/strong><\/a> \u00a0for further technical support and guidance.<\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
If you can\u2019t find the answer to your question please <\/span>contact us<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
prescribed for acute and chronic diseases with as many as 40 million surgeries
performed annually in the United States alone. Much of human surgery is
performed without any image guidance where the surgeon has only direct
visualizations as their guide. Fluorescence guided surgery (FGS), (also called
\u2018Fluorescence image-guided surgery\u2019) is a medical imaging technique used to
detect fluorescently labelled structures during surgery and provide real time
assessment of blood flow to these structures. Fluorescence Guided Surgery (FGS)
guides the surgical procedure and provides the surgeon with real time
visualization of their operating field.<\/span><\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t
a certain wavelength from a material when it is irradiated by light with
another wavelength. The irradiated and emitted lights are called \u201cExcitation
Light\u201d and \u201cFluorescence Light\u201d respectively. The material is called a
\u201cFluorescent Substance\u201d or \u201cfluorophore\u201d.<\/span><\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t
imaging such as CT and MRI scans, surgeons still almost exclusively operate
under white (visible) light during their procedures and must rely on their
ability to see and feel target tissues. Unfortunately, most human tissue looks
very similar under white light, and it can be very difficult to distinguish one
tissue from another or to completely remove a target tissue such as a tumor. In
addition, a surgeon can only see the uppermost layer of tissue under white
light while tissues and structures underneath will remain hidden.<\/span><\/p>
the surgeons the ability to \u2018see\u2019 these invisible structures by using a
different wavelength of light. By combining this visual ability with the
special dyes that fluoresce in those wavelengths, surgeons can much more
precisely target or avoid certain organs or tissues. In addition, the
near-infrared light used in FGS can more easily penetrate human tissues,
allowing surgeons to see \u2018through\u2019 layers of tissue and organs. FGS has the
added advantage of being a real-time imaging process. Whereas traditional
imaging like X-Rays, CT Scans, and MRI scans can provide excellent images, they
are all limited to providing static images.<\/span><\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t
Green (ICG). ICG is a tricarbocyanine dye with both hydrophilic and lipophilic
properties. Developed in the 1950s, Indocycanine Green (ICG) is a water-soluble
fluorescent molecule with a proven safety profile that binds to plasma
proteins.<\/span><\/p>
assessment of vascular perfusion (or blood flow) to the tissues and organs in
many areas of medicine. The light required to trigger fluorescence is generated
by a near-infrared light source attached to a camera, which tracks and
documents both absorption and fluorescence in real time.<\/span><\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t
territories worldwide. Marketed in many territories in Europe under the name
Verdye and in the USA by the name Indocyanine Green for Injection, USP, it is
sold internationally by Diagnostic Green.\u00a0 Diagnostic Green is the leading
provider of trusted high quality ICG for physicians worldwide.<\/span><\/p>
injection (I.V.) via an injection needle, a central or peripheral catheter or
cardiac catheter. Following I.V. administration, ICG is rapidly bound to plasma
proteins, of which beta-apolipoprotein B is the principle carrier (95%) and
remains in the blood vessels.\u00a0 ICG is cleared exclusively through the
liver, and then eliminated through the bile. It does not undergo metabolism.<\/span><\/p>
for fluorescence angiography purposes in various medical fields (ophthalmology,
microsurgery). As it is exclusively removed by the liver, it is also used for
liver function testing. Half-life after injection into blood is three-four
minutes, is rapidly bound to plasma protein and undergoes no significant
extrahepatic or enterohepatic circulation. Diagnostic procedures with ICG
should be performed under the supervision of a physician.<\/span><\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t
the near-infrared region where light absorption by hemoglobin (and water) is
small, so the light can travel long distances in the human body.\u00a0
Indocyanine Green (ICG) can be excited and emits fluorescence which can be
visualized by appropriate camera systems approved worldwide.<\/span><\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t
surgical field are obtained using a combination of filters, lenses and cameras.
During open surgery, hand-held devices are usually preferred for their ease of
use and mobility. Examples of hand-held systems include IC-Flow, PDE Neo and
Fluobeam. Fluoresence Guided Surgery (FGS) can also be performed using
minimally invasive devices such as laparoscopes or endoscopes. In this case, a
system of filters, lenses and cameras is attached to the end of the
probe.\u00a0 Examples of endoscopic camera systems include System Green, Visera Elite,
EleVision and Rubina\u2122. Fluorescence Guided Surgery (FGS) devices can also be
implemented for robotic surgery (for example in the da Vinci Surgical System).<\/span><\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t
benefits of low cost, ease of use, no reliance upon damaging ionizing radiation
and enhanced safety through visualization,\u201d said Michael Bouvet, MD, center Co-Director
and former president of the International Society of Fluorescence Guided
Surgery.<\/span><\/p>
game-changer for cancer surgeries,\u201d Dr Ann M Wallace, Director of the
Comprehensive Breast Health Center at UC San Diego Health.<\/span><\/p><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t