Clarifying Misconceptions About Iodine “Allergies” for Perioperative Patient Care

Iodine is a trace element that is required to produce thyroid hormone. Some preoperative skin antiseptics and contrast media that are used in a variety of specialties (eg, cardiovascular, urology) contain iodine. Clinicians and patients may believe that a history of a reaction to shellfish, povidone-iodine, or radiopaque contrast media is an allergy requiring avoidance of all three substances. Because iodine is required for life and does not stimulate an immune response, there is no relationship between iodine and adverse reactions to iodine-containing products. Perioperative nurses should have knowledge of allergies associated with iodine-containing substances and should assess patients for allergies.

During the assessment process, they can seek input on the cause of any previous reactions and share information on allergies with the patient. They also can collaborate with leaders and information technology personnel to update the electronic health record to avoid documentation of iodine as an allergen.

https://doi.org/10.1002/aorn.14267

Indocyanine green in left side colorectal surgery segmental resection to decrease anastomotic leak: A parallel retrospective cohort study of 115 patients

Background: We investigated the impact of Indocyanine Green (ICG) angiography on reducing anastomotic leakage (AL) after elective left segmental colon resection, including transverse resection. While ICG is widely used in colorectal surgery to assess vascularization, its true effect on AL, particularly in left segmental resections, remains unclear.

Study design: This retrospective, monocentric cohort study included patients undergoing left and transverse colon resection from January 2017 to July 2023. Patients were divided into ICG and no-ICG groups. The primary outcome was AL, with secondary outcomes including postoperative morbidity and length of stay.

Results: Of the 115 patients enrolled, 53 received ICG and 63 did not. AL occurred in 6 patients in the no-ICG group, but none in the ICG group. No significant correlation was found between ICG use and other confounding factors. Postoperative length of stay was also shorter in the ICG group.

Conclusions: The use of ICG was associated with a reduction in AL, with no cases in the ICG group. These findings suggest a potential benefit of ICG, warranting confirmation in future large-scale studies.

https://www.cell.com/heliyon/fulltext/S2405-8440(24)15761-1?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2405844024157611%3Fshowall%3Dtrue