In recent years, the rise of minimally invasive surgery has driven the development of surgical devices. Indocyanine green (ICG) fluorescence imaging is receiving increased attention in colorectal surgery for improved intraoperative visualization and decision-making. ICG, approved by the U.S. Food and Drug Administration in 1959, rapidly binds to plasma proteins and is primarily intravascular. ICG absorption of near-infrared light (750-800 nm) and emission as fluorescence (830 nm) when bound to tissue proteins enhances deep tissue visualization. Applications include assessing anastomotic perfusion, identifying sentinel lymph nodes, and detecting colorectal cancer metastasis. However, standardized protocols and research on clinical outcomes remain limited. This study explores ICG’s role, advantages, disadvantages, and potential clinical impact in colorectal surgery.

ICG-FI offers valuable visualization of vessels, lymphatics, and tumors in colorectal surgery. Its application has demonstrated promise in achieving favorable clinical outcomes, including a reduction in AL and improved lymphadenectomy. These findings emphasize the potential advantages of incorporating ICG-FI into colorectal surgical practice, providing enhanced intraoperative guidance and potentially leading to improved patient outcomes.

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