A cholecystectomy under complete fluorescence guidance (C-CFG) was performed. C-CFG was performed without switching to the white light mode. All procedures can be performed while visualizing the common bile duct. Peeling around the cystic duct was appropriately guided by ICG fluorescence. The line to be peeled is clearly recognized while being exfoliated from the liver. We report the execution of a cholecystectomy under complete fluorescence guidance using near-infrared camera images without switching to the white light mode, a method that has not been reported previously.